Manzini is a region of Swaziland, located in the center-west of the country. It has an area of 4,093.59 kmĀ² and a population of 319,530 (2007), and is divided into 16 tinkhundla. Its administrative center is Manzini. It borders all three other regions: Hhohho in the north, Lubombo in the east, and Shiselweni in the south. It is bordered by the Mpumalanga province in South Africa to the west.